Has any section of the I-10 been closed like what is happening right now? It’s closed from Alameda St. to Santa Fe Ave in Downtown LA due to a major fire underneath the interstate on 14th St. It damaged the structure of the freeway so the I-10 is closed in both directions from Alameda St. to Santa Fe Ave. until further notice. The only thing that comes to mind is the 101 near Santa Barbara from the flooding, which lasted for many months.